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Valine

Rating: Good

Benefits: Hydration, Soothing,

Categories: Humectant,

Valine at a Glance

  • An essential amino acid that provides hydrating benefits
  • One part of a soothing peptide also made of lysine and proline
  • Works in the body with leucine and isoleucine to synthesize collagens
  • May be animal-derived or synthetic

Valine Description

Valine is an amino acid that’s considered essential for health since the body is unable to manufacture it so this amino must be obtained via food or supplements. It may be animal-derived or synthetic, with Paula’s Choice Skincare using the latter form.

Valine has soothing properties when combined with amino acids lysine and proline to form a peptide. It works in the body by aiding the synthesis of the skin’s primary collagens, those being 1 and 3.

Research hasn’t shown topical application of valine promotes collagen formation, although as with most of the essential aminos, it helps improve skin hydration by improving its natural moisturizing factor (NMF).

Usage levels of valine in skin care range from 0.00004%–0.5% in leave-on products, with rinse-off formulas containing up to 1%.

Valine References

Bioscience, Biotechnology and Biochemistry, April 2018, pages 611–615

Journal of Pharmaceutical Sciences, July 2017, pages 1,814–1,820

International Journal of Toxicology, November 2013, pages 41S–64S

Peer-reviewed, substantiated scientific research is used to assess ingredients in this dictionary. Regulations regarding usage constraints, permitted concentration levels and availability vary by country and region.
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