Teprenone at a Glance
- Has antioxidant properties
- Also an anti-inflammatory agent
- Can inhibit melanin synthesis
- Also called geranylgeranylacetone
Teprenone Description
Teprenone, also known as geranylgeranylacetone, is a type of compound known as an acylic polyisoprenoid, a linear rather than a cyclic, ring-shaped molecule. Since 1984, it has been used as a treatment for gastric ulcers in Japan and other Asian countries under the brand name Selbex.
In addition to its gastro-protective properties, science has found teprenone useful in a variety of additional applications. Of note is its antioxidant and anti-inflammatory properties, indicating usefulness when it comes to anti-aging. A recent study even found that teprenone has the ability to inhibit melanin synthesis, meaning it could become an effective treatment for skin discolorations caused by the overproduction of melanin.
From a skin longevity standpoint, teprenone seems to play a role in reducing multiple intrinsic factors that can cause skin to look prematurely aged, especially from direct exposure to UV light. As such, it may have benefits for restoring a firmer, less lined look and feel to damaged skin.
The recommended use level of teprenone in cosmetics is 3% when combined with the emollient caprylic/capric triglyceride.
Teprenone References
PubChem.com, Website, Accessed November 2024
ScienceDirect.com, Website, Accessed November 2024
International Immunopharmacology, June 2024, ePublication
Antioxidants, August 2023, pages 1-18
Life Sciences, June 2015, pages 51-56 and August 2013, Pages 226-232