Palmitoyl Tetrapeptide-7 at a Glance
- Composed of four amino acids + palmitic acid
- Can fight factors in skin that cause irritation
- Ongoing use helps restore a firmer feel
Palmitoyl Tetrapeptide-7 Description
Palmitoyl tetrapeptide-7 is a synthetic peptide composed of the amino acids glutamine, glycine, arginine, and proline. It works as a skin-restoring ingredient and is noted for its soothing ability since it can interrupt factors within skin that lead to signs of irritation (including from exposure to UVB light) and loss of firmness. By working in this manner, skin can regain a firm feeling and engage in repair so that wrinkles will be visibly reduced.
Along with the four amino acids, this peptide also contains the fatty acid palmitic acid to enhance stability and penetration into the skin. Typical usage level is in the parts per million range, which translates to very low, yet highly effective percentages between 0.0001%–0.005%, although higher or lower amounts may be used depending on the formulary goals.
Palmitoyl tetrapeptide-7 is often used as part of a blend with other peptides, such as palmitoyl tripeptide-1. This can produce a nice synergy and offer more targeted results on a wider range of skin concerns.
On its own, it is supplied as a powder but in blends it’s combined with hydrators like glycerin, various glycols, triglycerides, or fatty alcohols to make them easier to incorporate into formulas.
The Cosmetic Ingredient Review Expert Panel assessed this water-soluble peptide in 2018 alongside other peptides and conclued that this ingredient is safe as used in cosmetics.
Palmitoyl Tetrapeptide-7 References
Cosmetics, November 2020, ePublication
International Journal of Toxicology, Volume 37, Supplement 3, November 2018, pages 90S–102S
Journal of Cosmetic Dermatology, June 2015, pages 152–160
Molecular Pharmaceutics, March 2013, pages 1,063-1,069
Plastic Surgical Nursing, April 2012, pages 71–72