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Ascorbyl Palmitate

Rating: Best

Benefits: Anti-Aging, Dark Spot Fading, Evens Skin Tone,

Categories: Antioxidant,

Ascorbyl Palmitate at a Glance

  • Made by combining ascorbic acid with palmitic acid
  • Has a powerful synergy with vitamin E
  • Exhibits antioxidant benefits
  • Not considered as effective as pure vitamin C
  • Often used to help stabilize air-sensitive skin care ingredients
  • Also used as a food additive to improve stability of oils

Ascorbyl Palmitate Description

Ascorbyl palmitate is a stable, oil-soluble form of vitamin C that is made by combining ascorbic acid with a fatty acid known as palmitic acid. It’s also known as ascorbyl-6 palmitate, and it is effective up to a pH of 6. Pure vitamin C (ascorbic acid) requires a pH of 3.5 or lower to work, making ascorbyl palmitate easier to formulate with.

Although ascorbyl palmitate has antioxidant benefit for skin, research has shown it doesn’t penetrate as well as pure vitamin C (ascorbic acid) and that its conversion to vitamin C isn’t as efficient as other forms (such as tetrahexyldecyl ascorbate). This helps explain why ascorbyl palmitate isn’t the leading form of vitamin C in products meant to address lack of firmness, wrinkles, and discolorations. Research has shown that a modified form of this ingredient, known as trisodium ascorbyl-6 palmitate 2-phosphate overcomes this conversion issue.

The palmitate portion of this ingredient lends it hydrating properties many other forms of vitamin C do not have.

Interestingly, although ascorbyl palmitate is considered a stable form of vitamin C, research has shown other forms possess greater stability and skin can more freely convert those forms to ascorbic acid. However, a comparative study showed that ascorbyl palmitate maintains adequate stability in different types of emulsions when it is encapsulated.

Ascorbyl palmitate is often used in skin care at amounts between 0.1-1% where its antioxidant ability helps stabilize more delicate ingredients, including pure vitamin C; however, it’s not impervious to breaking down with ongoing exposure to heat and oxygen, as data from multiple ingredient suppliers attests.

suggested that ascorbyl palmitate can cause oxidative damage to skin when the lipid (palmitate) portion oxidizes upon exposure to UVB light. However, it’s important to note that the irradiated keratinocytes (skin cells) in this study weren’t treated with any UV filter, only the ascorbyl palmitate. In essence, this is like testing an umbrella’s ability to keep you dry on a sunny day without rain. The results are inconclusive without a proper control (rain, or, in the case of this study, a UV filter) to measure against. This study also didn’t show what would happen if other antioxidants such as green tea were in the mix.

Ascorbyl Palmitate References

International Journal of Toxicology, 2022, pages 57S-75S

The Journal of Clinical and Aesthetic Dermatology, July 2017, pages 14-17

Drug Research, January 2017, pages 52-58

Nutrients, July 2017, ePublication

Acta Poloniae Pharmaceutica, September 2016, pages 1,339-1,349

International Journal of Cosmetic Science, December 2008, pages 453-458

Pharmazie, October 2005, pages 751-755

European Journal of Pharmaceutics and Biopharmaceutics, July 2003, pages 59-66

Journal of Investigative Dermatology, November 2002, pages 1,103-1,108

Journal of Pharmaceutical and Biomedical Analysis, March 1997, pages 795-801

Peer-reviewed, substantiated scientific research is used to assess ingredients in this dictionary. Regulations regarding usage constraints, permitted concentration levels and availability vary by country and region.
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